What is a Center of Clinical Investigation?

The Centers of Clinical Investigation (CIC) are public structures placed under the double supervision of the National Institute for Health and Medical Research (INSERM) and the Hospitalization Direction and the Treatment Organization (DHOS). They are completely dedicated to the organization, coordination and realization of clinical trials.

The CIC 1417 Cochin-Pasteur

Being the only Center of Clinical Investigation exclusively dedicated to the vaccine research in France, our team collaborates with researches, doctors, industrials and associations in order to elaborate new, better tolerated and more effective vaccines.

Situated in the heart of Cochin hospital in Paris, our investigation center joins all the essential competences to undertake this challenge, narrowly linked to the clinical services of the hospital.

Coordinated by the Professor Odile Launay working with the Doctors Paul Loubet and Marie Lachâtre, the CIC Cochin-Pasteur is an original structure, in which conjointly work medical investigators, clinical research nurses and a medical secretary. […]

The research of new vaccines being a worldwide health issue, the CIC Cochin-Pasteur takes part in it very actively, applying a rigorous quality approach, in order to implement and assure the security of our participants, as well as ensuring the “good health practices” and improving everyday our skills and services.

Nowadays as well, during the outburst of the Covid-19 pandemic, the Center of Clinical Investigation 1417 Cochin-Pasteur increases its efforts.

When has it been established?

Established in XXX and formerly named Center of Vaccines Trials, the organism has engaged itself in the realization of clinical trials in the domain of research.

In 2002, the center functionally associates to the Pasteur Institute and becomes the Center Cochin-Pasteur of Vaccines Trial. This association allows the center to proceed to the realization of vaccine trials having a preventive and therapeutic purpose.

In 2005, as part of the INSERM and DHOS’s integrated CIC’s tender in biotherapy, the CIC Cochin-Pasteur acquires the label of a CIC in vaccinology integrated in biotherapy. In 2007, the CIC in Vaccinology Cochin-Pasteur (CIC BT505) becomes a mixed INSERM/DHOS strcture dedicated to the vaccinology research and which organization is formalized by convetion with its different partners : INSERM, the Pasteur Institute and the Faculty of medicine Paris-Descartes.

In 2014, the CIC BT505 receives a new identity and becomes the CIC 1417 Cochin-Pasteur.

The biomedical researches carried out at the CIC 1417 are realized in accordance with international rules on protection of people carrying out this type of research.

The CIC 1417 benefits of an authorization lieu delivered by the ANSM. This authorization habilitates and allows the conduct of biomedical research, especially for adult volunteers and underage volunteers starting from 1 month.

The CIC 1417 works in narrow collaboration with academic research structures, specialized clinical services, public and private laboratories. The biomedical researches needing the use of animals in the procedure of the project, cannot benefit of the center’s organization and structure.

Interview

Pr Daniel Floret

Président du comité technique des vaccinations
(CTV) professeur émérite de pédiatrie à l’Université Claude Bernard de Lyon

Que pensez-vous des initiatives du CIC de vaccinologie de l’hôpital Cochin ?

Il me semble réellement très important que des acteurs académiques soient capables de mener des essais cliniques sur les...

Pr Philippe Sansonetti

Professeur au Collège de France
Professeur à l’Institut Pasteur
Directeur de l’Unité de Pathogénie Microbienne Moléculaire, Unité INSERM 1202, Institut Pasteur.

Comment Cochin et Pasteur sont-ils devenus partenaires dans la recherche sur les vaccins ?

L’action concertée entre Cochin et Pasteur a démarré en 1998 dans le domaine des maladies infectieuses...

History