Activités de recherche
Etudes institutionnelles en cours
* Attitudes et pratiques vaccinales des médecins spécialistes hospitaliers « SPECIVAC » APHP
* Efficacy study of the quadrivalent Human Papilloma Virus (HPV) vaccine to prevent recurrence of External Genital Warts (EGW) in patients who were cured in the first place “CONDYVAC” APHP
* Evaluation of immunological Response Following a Revaccination with PPS23 Bossted or not by PCV13 in splenectomised Patients “SPLENEVAC-2” APHP
* Efficacité en population de la vaccination antigrippale saisonnière pour la prévention des grippes de l’adulte hospitalisé "FLUVAC EV-03" INSERM
Etudes institutionnelles
* Cohort Study of Volunteers That Have Participated to Preventive HIV-1 Vaccine Trials (COHVAC, NCT00789789) ANRS »
* Multicenter Pilot Study Evaluating the Immunogenicity of an Innovative Pneumococcal Vaccination Strategy in Splenectomized Adults (SPLENEVAC, NCT02052154) APHP »
* Safety and Immunogenicity of Recombinant Pichia Pastoris AMA1-DiCo Candidate Malaria Vaccine With GLA-SE and Alhydrogel ® as Adjuvant in Healthy Malaria Non-Exposed European and Malaria Exposed African Adults (AMA1-DiCo, NCT02014727) »
* Open Randomized Trial Evaluating Four Anti-pneumococcal Vaccine Strategies With Fractionated Doses of Non Conjugate Polysaccharide Vaccine to Prevent Hyporesponse in Healthy Volunteers (HYPOPNEUMO, NCT02279589) APHP »
* Clinical Trial to Assess the Influenza Vaccination for Seasonal 2013-2016 (FLUVAC EV-03, NCT02027233) INSERM »
* Vemurafenib and Cobimetinib Combination in BRAF Mutated Melanoma With Brain Metastasis (CONVERCE, NCT02537600) Center Eugene Marquis »
* Trial to Evaluate the Safety and Immunogenicity of a Placental Malaria Vaccine Candidate (PRIMVAC ) in Healthy Adults (PRIMALVAC, NCT02658253) INSERM »
* GeneTB « Etude de l’influence de la génétique sur la prédisposition à la tuberculose » Institut Pasteur
* Changing the coUrse of cRohn’s disease with an Early use of adalimumab:
The CURE study Groupe d’Etude Thérapeutique des Affections Inflammatoires Digestives (G.E.T.A.I.D.)
* ETUDE ANRS RF003 « IFN-VIH » Etude des sous types d’interférons de type I et de type
III produits par les cellules de sang périphérique de patients infectés par le VIH ANRS
* ANRS RF 002 INTESTIPAX DESEQUILIBRE IL-23 /IL-12 ET POLARISATION t INTESTINALE DANS L’INFECTION PAR VIH IL-23/IL-12 Imbalance and T Lymphocyte Polarization in HIV Infection (INTESTIPAX) (NCT01942655) ANRS »
Page en cours d'actualisation
Essais industriels en cours :
- Changing the coUrse of cRohn’s disease with an Early use of adalimumab: The CURE study - Groupe d’Etude Thérapeutique des Affections Inflammatoires Digestives (G.E.T.A.I.D.)
- A Prospective Non-Interventional Study of Bleeding Episodes, Factor VIII Infusions, and Patient-Reported Outcomes in Individuals with Severe Hemophilia A - BIOMARIN
Essais industriels :
- A Study to Evaluate the Safety and Efficacy of Inactivated Varicella-zoster Vaccine (VZV) as a Preventative Treatment for Herpes Zoster (HZ) and HZ-related Complications in Adult Participants With Solid Tumor or Hematologic Malignancy (V212-011, NCT 01254630) Merck »
- Study to Evaluate the Safety and Efficacy of Two Different Dosing Schedules of Pembrolizumab (MK-3475) Compared to Ipilimumab in Participants With Advanced Melanoma (MK-3475-006/KEYNOTE-006, NCT01866319) Merck »
- A Study of the BRAF Inhibitor Dabrafenib in Combination With the MEK Inhibitor Trametinib in the Adjuvant Treatment of High-risk BRAF V600 Mutation-positive Melanoma After Surgical Resection. (COMBI-AD) (NCT01682083) GSK »
- Safety, Tolerability and Immunogenicity Induced by the THV01 Treatment in Patients Infected With HIV-1 Clade B and Treated With Highly Active Antiretroviral Therapy (HAART). (NCT02054286)Theravectys S.A. »
- Study of a Candidate Clostridium Difficile Toxoid Vaccine (Cdiffense) in Subjects at Risk for C. Difficile Infection (NCT01887912) Sanofi Pasteur »
- Open-label, Phase I/IIa Study of VAC-3S in HIV-1 Patients Who Showed an Immune Response to VAC-3S During IVVAC-3S/P1 (NCT02390466) InnaVirVax »
- Access Study of Trametinib for Subjects With Advanced Unresectable (Stage IIIc) or Distant Metastatic (Stage IV) BRAF V600E/K Mutation Positive Cutaneous Melanoma (NCT02416232) GSK »
- Study of Pembrolizumab (MK-3475) Versus Placebo After Complete Resection of High-Risk Stage III Melanoma (MK-3475-054/KEYNOTE-054) (NCT02362594) Merck »
- Safety and Efficacy of SA4Ag Vaccine in Adults Having Elective Open Posterior Spinal Fusion Procedures With Multilevel Instrumentation (STRIVE) (NCT02388165) Pfizer »
- A Study to Assess Safety Tolerability and Immunogenicity of Three Prime-boost Regimens of the Candidate Prophylactic Vaccines for Ebola in Healthy Adults (NCT02416453) Crucell Holland BV »
- A Study to Evaluate the Pharmacokinetics, Safety, and Antiviral Activity of JNJ-63623872 in Combination With Oseltamivir in Adult, and Elderly Hospitalized Participants With Influenza A Infection (NCT02532283) anssen Research & Development, LLC »